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Cartilage ECM cell culture substrates

Cartilage ECM cell culture substrates

Extracellular matrix (ECM) is a major component of the cell microenvironment with important signaling and regulatory functions. Derived from healthy acellular porcine hyaline cartilage, TissueSpec® cartilage matrix is rich in type II collagen with fibrous proteins, proteoglycans, hyaluronic acid (HA), and chondroitin sulfate that together regulate chondrogenesis, chondrocyte differentiation, response to mechanical stimulation, matrix remodeling, metabolism, and survival and provide biomechanical signals through cell-matrix interactions.

TissueSpec® Cartilage Hydrogels supported the chondrogenic differentiation of mesenchymal stem cells, which formed cartilageous tissue constructs and demonstrated increased mechanical stiffness and biochemical properties resembling native articular cartilage.

Item: MTCT101 TissueSpec® ECM Hydrogel Kit Instructions for use
Item: MTCT201
NativeCoat™ ECM Surface Coating Kit
Instructions for use
Item: MTCT300 TissueSpec® ECM Scaffold (custom)

 

TissueSpec® Matrix Kits

Extracellular matrix (ECM) hydrogel or solution kit. Trial size available.

Contact us to discuss your application and pricing options.
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Custom Matrix Formats

TissueSpec® ECM scaffolds are available through custom order. East River Bio also specializes in isolating extracellular matrix from additional tissues or specific regions within tissues of interest as well as other sources (e.g., human).